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The normal development of an organism depends on the precise orchestration of cell division, differentiation and morphogenesis. Much is understood about how developmental regulatory genes affect cell differentiation, but little is understood about how they control cell proliferation throughout development. Using genetic analysis and molecular approaches in聽C. elegans, the Roy lab is engaged in the identification and characterization of both novel and previously known genes, which affect cell division throughout the course of postembryonic development in聽C. elegans.