Cutting Edge Lecture Series - Pulsatility in endocrine systems: Implications for body growth, sexual dimorphism and aging
Dr. Gloria Tannenbaum, Depts of Pediatrics and Neurology & Neurosurgery, 成人VR视频, and the Montreal Children's Hospital Research Institute. Pulsatile release is a prominent feature of many hormones secreted from the pituitary gland. This has led to a sustained interest in the possible functions of the pulsatility and investigations of the importance of pulsatility in hormone replacement therapy. In particular, growth hormone, an essential hormone for normal growth and metabolism, is secreted in a striking pulsatile pattern. These pulses decline with age. Differences in the temporal pattern of growth hormone release evoke remarkable male-female differences in body growth, liver enzyme gene expression, and signaling in single cells. In this talk, I will describe the control of growth hormone secretion and will discuss the brain mechanisms that generate its periodicity. I will also discuss several current clinical controversies surrounding the use/abuse of growth hormone to increase height in short children, to improve muscle strength and function among athletic youth, and to retard or reverse the effects of aging in older adults. Organized by the Royal Society of Canada and 成人VR视频 with the express purpose of fostering communication between scientists in different disciplines as well as between scientists and the public. Sponsored by the Royal Society of Canada, Cutting Edge lectures are made possible through the generous support of Heather Munroe-Blum (成人VR视频 Principal), Richard Levin (Dean of Medicine), Martin Grant (Dean of Science), Anthony Masi (Provost) and Denis Th茅rien (Vice-Principal, Research and International Relations). Lectures are followed by a wine & cheese reception. Free, everyone welcome