BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260222T045951EST-2049k5zPPU@132.216.98.100 DTSTAMP:20260222T095951Z DESCRIPTION:Abstract: \n\n Severe traumatic fractures frequently require op en surgical interventions\, where current fixation and regenerative strate gies often lack adaptability to patient-specific needs. These procedures a re also associated with a substantial risk of post-operative infection\, h ighlighting the need for materials that can simultaneously support tissue repair while mitigating bacterial colonization. In this seminar\, I will p resent our work on the design of precision polymer networks based on dendr itic macromolecular building blocks and thiol–allyl-terminated triazine tr ione (TATO) monomers\, using blue-light triggered thiol–ene chemistry as s urgically viable on-demand crosslinking strategy. The proposed approach en ables network formation under mild conditions and allows control over netw ork architecture\, crosslink density\, and functional group presentation. Examples will include hydrolytically degradable\, light-curable networks\, yielding both charged and neutral materials. Applications relevant to fra cture fixation\, bone regeneration and infection control will be highlight ed\, including antibiotic-free antibacterial polymer networks. Emphasis wi ll be placed on structure–property relationships and on how molecular desi gn and thiol–ene network formation influence material and biological perfo rmance.\n\n \n\nBio:\n\nDr. Michael Malkoch is Professor of Functional Org anic Nanomaterials at KTH Royal Institute of Technology\, where he leads r esearch at the interface of polymer chemistry\, materials science\, and bi omedical engineering. He has received major competitive funding from the S wedish Research Council (VR) and the Knut and Alice Wallenberg Foundation\ , reflecting long-term support for fundamental and translational research in macromolecular design. The research of the Malkoch group focuses on the development of well-defined macromolecular architectures and precision po lymer networks with controlled structure–property relationships. A central theme is the use of modular and efficient chemistries including thiol-ene /yne click reactions to enable spatiotemporal control over network formati on under mild\, biologically compatible conditions. These strategies allow the tailoring of mechanical performance\, degradation behaviour\, and bio logical function across a range of soft and hard tissue applications. Curr ent research directions include light-curable materials for tissue fixatio n and regeneration\, antibiotic-free antibacterial polymers and hydrogels designed to address challenges associated with bacterial resistance\, and nanoscopic delivery systems based on dendritic and oligomeric platforms. H is work spans molecular synthesis\, materials characterization\, and biolo gical evaluation\, with an emphasis on robustness\, scalability\, and tran slational relevance. Dr. Malkoch has authored approximately 150 peer-revie wed publications and is an inventor on more than 20 patents. He is activel y involved in interdisciplinary collaborations and the training of graduat e students and postdoctoral researchers in polymer chemistry and functiona l materials science. \n DTSTART:20260224T180000Z DTEND:20260224T193000Z LOCATION:OM 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\, 801 rue Sherbrooke Ouest SUMMARY:³ÉÈËVRÊÓƵ Chemical Society Seminar Series- Michael Malkoch: Blue-light triggered thiol–ene/yne chemistry of crosslinked networks suited for hard -tissue regeneration and infection control URL:/channels/channels/event/mcgill-chemical-society-s eminar-series-michael-malkoch-blue-light-triggered-thiol-eneyne-chemistry- 371196 END:VEVENT END:VCALENDAR