成人VR视频

Accueil
脡惫猫苍别尘别苍迟

Killam Seminar Series: Microfluidic tools for studying cell-cell interactions

Mardi, 20 蹿茅惫谤颈别谤, 2024 16:00脿17:00
Montreal Neurological Institute de Grandpre Communications Centre, 3801 rue University, Montreal, QC, H3A 2B4, CA

Gr芒ce 脿 la g茅n茅rosit茅 des fiducies Killam, Le Neuro convoque lors d鈥檜ne s茅rie de s茅minaires des conf茅renciers d鈥檈xception dont les travaux passionnent ses chercheurs et ceux de l鈥橴niversit茅 成人VR视频.听

Pour participer en personne, inscrivez-vous听

Pour visionner la diffusion sur Vimeo, cliquez sur le lien

Iain Clark

Professeur adjoint, bio-ing茅nierie, UC Berkeley, 脡tats-Unis

贬么迟别:听jo.stratton [at] mcgill.ca (Jo Anne Stratton)

Abstract:听Central nervous system (CNS)-resident astrocytes and microglia interact to regulate pro-inflammatory programs that drive neurodegenerative diseases, but the pathways and molecules involved are largely unknown. Understanding the language of inflammation is a central question in the field of Neuroimmunology and may guide new therapeutic approaches for multiple sclerosis (MS) and other neurologic diseases. Interactions between CNS-resident cells are highly heterogeneous; astrocytes and microglia nourish and protect neurons, while inflammatory subsets drive demyelination and neurodegeneration in neurologic diseases. We recently developed two novel approaches to study astrocyte-microglia interactions at the single-cell level during inflammation: 1) an in vivo barcoding-based strategy that analyzes the transcriptomes and connections between individual cells, and 2) a droplet-based platform for genome-wide, unbiased CRISPR/Cas9 screening of genes that mediate cell crosstalk. In this seminar, I will discuss the development of these technologies and their application to study astrocyte-microglia signaling in experimental autoimmune encephalomyelitis (EAE), a preclinical mouse model of MS.

Liens connexes

Iain Clark

Iain C. Clark is an Assistant Professor in the Bioengineering Department at the University of California, Berkeley, and a faculty affiliate at the California Institute for Quantitative Biosciences. Research in the Clark lab combines tools from multiple disciplines - molecular biology, microfluidics, engineering, and bioinformatics - to study infectious diseases, central nervous system inflammation, and neural circuit connectivity.

颁辞辞谤诲辞苍苍茅别蝉

Contact: 
Justin Martinez-Rosler
Organisation: 
成人VR视频 (The Neuro)
Courriel: 
justin.martinez-rosler [at] mcgill.ca
颁补迟茅驳辞谤颈别:&苍产蝉辫;
ven, 02/09/2024 - 14:06
Site de source: 
/neuro

Le Neuro听成人VR视频

听

Le Neuro (L'Institut-H么pital neurologique听de Montr茅al) - un institut de recherche et d鈥檈nseignement bilingue de 成人VR视频, qui offre des soins de haut calibre aux patients - est la pierre angulaire de la Mission en neurosciences du Centre universitaire de sant茅 成人VR视频. Nous sommes fiers d鈥櫭猼re une institution Killam, soutenue par les fiducies Killam.

听

听

Back to top