Hyman M Schipper, MD, PhD, FRCPC
Professor
Senior Investigator, Lady Davis Institute
Dr. Schipper received his M.D. and Ph.D. (Neuroendocrinology) degrees at 成人VR视频 in 1982. He studied Internal Medicine at 成人VR视频, Neurology at Columbia University, and Endocrinology at Tufts University. Dr. Schipper is currently tenured Professor of Neurology and Medicine (Geriatrics) at 成人VR视频, staff neurologist at the Jewish General Hospital, and consultant at other Montreal institutions. He is founding director of the Centre for Neurotranslational Research, a Biomedical Redox Laboratory and the Alzheimer Risk Assessment Clinic at the Jewish General Hospital, and a founding scientist of Molecular Biometrics Inc.
Dr. Schipper鈥檚 long-standing research interests are in the fields of oxidative stress, brain aging and neurodegenerative diseases. Three papers (1980-3) emanating from his doctoral thesis provided the earliest published evidence that chronic exposure to ovarian estrogen promotes aging-related degenerative changes in rodent brain regions implicated in reproductive senescence and the development of polycystic ovaries. Since 1990, his laboratory has contributed a large body of evidence and novel theory concerning the role of heme oxygenase-1 (HO-1) and iron-containing astroglia in CNS senescence and free radical-related neurodegenerative disorders. A major research focus of his laboratory is the development of blood-based biological markers for the early diagnosis and prognosis of sporadic Alzheimer disease and other degenerative human CNS afflictions. Dr. Schipper鈥檚 laboratory has received generous support from the Canadian Institutes for Health Research, the聽Fonds de la recherche en sant茅 du Qu茅bec聽and several other Canadian and American funding agencies. Dr. Schipper has published over 170 articles on various aspects of the redox neurosciences and related topics in peer-reviewed journals and is an inventor on聽twelve patents. In 1998, he edited聽the first book of its genre, entitled聽Astrocytes in Brain Aging and Neurodegeneration聽(RG Landes Co.). He co-edited a volume for the聽Annals of the New York Academy of Sciences聽on brain metals in 2004,聽and聽recently co-edited a 3-volume text entitled聽Principles of Free Radical Biomedicine聽(2012).聽He served on the Editorial Board of the聽Journal of Neurochemistry聽and is a member of numerous professional societies. He has given over 130 invited lectures, seminars, and presentations in Canada, the United States, Europe, and Israel. At 成人VR视频 and the Jewish General Hospital, Dr. Schipper provides basic and clinical teaching in the neurosciences and coordinates an interdisciplinary course on Free Radical Biomedicine in the Faculty of Science.
Oxidative stress, brain aging and neurodegenerative diseases