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Animal models, especially transgenic rodent models, have enhanced our understanding of cardiovascular function at the molecular level. Yet, they come with some limitations in their relevance to human health and the suitability to assess personalized responses to treatment.

In this talk, several technological approaches will be outlined to illustrate how we can build a pipeline for manipulating and characterizing human stem-cell-derived cardiomyocytes (iPSC-CMs) in a high-throughput manner. The techniques involve microfluidics, non-contact optical methods for functional analysis coupled with newer scalable gene and protein quantification methods. These efforts are meant to contribute to building a compelling framework for testing pharmacological and gene therapies for personalized medicine.

This seminar will be given online via Zoom. Details in attached poster.