2022
Gaither C, Popp R, Zahedi RP, Borchers CH. Multiple reaction monitoring-mass spectrometry enables robust quantitation of plasma proteins regardless of whole blood processing delays that may occur in the clinic. MCP. 2022 Feb 17. doi.org/10.1016/j.mcpro.2022.100212
Jennings MJ, Kagiava A, Vendredy L, Spaulding EL, Stavrou M, Hathazi D, Gr眉neboom A, De Winter V, Gess B, Schara U, Pogoryelova O, Lochm眉ller H, Borchers CH, Roos A, Burgess RW, Timmerman V, Kleopa KA, Horvath R.听NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice.听Brain. 2022 Feb 10;awac055. doi: 10.1093/brain/awac055.
Brzhozovskiy A, Kononikhin A, Bugrova AE, Kovalev GI, Schmit PO, Kruppa G, Nikolaev EN, Borchers CH.听The Parallel Reaction Monitoring-Parallel Accumulation-Serial Fragmentation (prm-PASEF) Approach for Multiplexed Absolute Quantitation of Proteins in Human Plasma.听Anal Chem. 2022 Jan 18. doi: 10.1021/acs.analchem.1c03782.
Petrotchenko EV, Borchers CH. Protein Chemistry Combined with Mass Spectrometry for Protein Structure Determination. Chem Rev. 2021 Dec 30. doi: 10.1021/acs.chemrev.1c00302
2021
Gaspar VP, Ibrahim S, Zahedi RP, Borchers CH. Utility, promise, and limitations of liquid chromatography-mass spectrometry-based therapeutic drug monitoring in precision medicine. Journal of Mass Spectrometry. 2021 Oct.
Serpa JJ, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Structure of prion 尾-oligomers as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations. Proteomics. 2021 Sep听5:e2000298. doi: 10.1002/pmic.202000298
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Ibrahim S, Lan C, Chabot C, Mitsa G, Buchanan M, Aguilar-Mahecha A, Elchebly M, Poetz O, Spatz A, Basik M, Batist G, Zahedi RP, Borchers CH.听Precise Quantitation of PTEN by Immuno-MRM: A Tool To Resolve the Breast Cancer Biomarker Controversy. Anal Chem. 2021 Jul 29. doi:10.1021/acs.analchem.1c00975听听
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听Gaither C,听Popp R, Borchers SP, Skarphedinsson K, Eiriksson FF, Thorsteinsdottir M, Mohammed Y, Borchers CH.听Performance Assessment of a 125 Human Plasma Peptide Mixture Stored at Room Temperature for Multiple Reaction MonitoringMass Spectrometry.听J. Proteome Res.听2021 July 16.听
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Laselva O,听Qureshi Z,听Zeng ZW,听Petrotchenko EV,听Ramjeesingh M,听Hamilton CM,听Huan LJ,听Borchers CH, Pomes R,听Young R,听Bear1 CE.听Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator.听iScience. 2021 June 25; 24 (6):102542.听
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Tran JN, G眉nther OP, Sherwood KR, Fenninger F, Allan LL, Lan J, Sapir-Pichhadze R, Duquesnoy R, Claas F, Marsh SGE, McMaster WR, Keown PA.听High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation.听Genome Canada Transplant Consortium. Commun Biol. 2021 May 14;4(1):583. doi: 10.1038/s42003-021-01989-3. PMID: 33990681 Free PMC article.
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Percy AJ, Borchers CH.听Detailed Method for Performing the ExSTA Approach in Quantitative Bottom-Up Plasma Proteomics. Methods Mol Biol. 2021;2228:353-384. doi: 10.1007/978-1-0716-1024-4_25. PMID: 33950503
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Li FKK, Gale RT, Petrotchenko EV, Borchers CH, Brown ED, Strynadka NCJ.听Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in听Staphylococcus aureus听wall teichoic acid biogenesis. J听Struct听Biol. 2021 Apr;听
2020
Michaud SA, P臎tro拧ov谩 H, Jackson AM, McGuire JC, Sinclair NJ, Ganguly M, Flenniken AM, Nutter LMJ, McKerlie C, Schibli D, Smith D, Borchers CH. Process and Workflow for Preparation of Disparate Mouse Tissues for Proteomic Analysis. J Proteome Res. 2021 Jan 1;20(1):305-316. doi: 10.1021/acs.jproteome.0c00399. Epub 2020 Nov 5. PMID: 33151080
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Gaspar VP, Ibrahim S, Sobsey CA, Richard VR, Spatz A, Zahedi RP, Borchers CH.听Direct and Precise Measurement of Bevacizumab Levels in Human Plasma Based on Controlled Methionine Oxidation and Multiple Reaction Monitoring.听ACS Pharmacol. Transl. Sci. 2020 Nov. 13.;doi.org/10.1021/acsptsci.0c00134
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Michaud SA, P臎tro拧ov谩 H, Jackson AM, McGuire JC, Sinclair NJ, Ganguly M, Flenniken AM, Nutter LMJ, McKerlie C, Schibli D, Smith D, Borchers CH. Process and Workflow for Preparation of Disparate Mouse Tissues for Proteomic Analysis. J Proteome Res. 2020 Nov 5. doi: 10.1021/acs.jproteome.0c00399. Online ahead of print. PMID: 33151080
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Marco GD, Jarrett KE, Burton JC, Doerfler AM, Hurley A, Li A, Hsu RH, Furgurson M, Patel KR, Han J, Borchers CH, Lagor WR.听Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA Reductase.听J. Lipid Res.听jlr.RA120001006.听First Published on听October 27, 2020,听doi:10.1194/jlr.RA120001006
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Leitner A, Bonvin AMJJ, Borchers CH, Chalkley RJ, Chamot-Rooke J, Combe CW, Cox J, Dong MQ, Fischer L, G枚tze M, Gozzo FC, Heck AJR, Hoopmann MR, Huang L, Ishihama Y, Jones AR, Kalisman N, Kohlbacher O, Mechtler K, Moritz RL, Netz E, Novak P, Petrotchenko E, Sali A, Scheltema RA, Schmidt C, Schriemer D, Sinz A, Sobott F, Stengel F, Thalassinos K, Urlaub H, Viner R, Vizca铆no JA, Wilkins MR, Rappsilber J.听Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. Structure. 2020 Oct 12:S0969-2126(20)30336-1. doi: 10.1016/j.str.2020.09.011
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Kopczynski D, Hentschel A, Coman C, Schebb NH, Hornemann T, Mashek DG, Hartung NM, Shevchuk O, Sch枚tt HF, Lorenz K, Torta F, Burla B, Zahedi RP, Sickmann A, Kreutz MR, Ejsing CS, Medenbach J, Ahrends R. Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. Anal Chem. 2020 Oct 20;92(20):13672-13676. doi: 10.1021/acs.analchem.0c02793. Epub 2020 Sep 21.PMID:32865986
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Richard VR, P Zahedi RP,Eintracht S,Borchers CH.An LC-MRM assay for the quantification of metanephrines from dried blood spots for the diagnosis of pheochromocytomas and paragangliomas. Anal Chim Acta.2020 Sep 1;1128:140-148.doi: 10.1016/j.aca.2020.06.020.Epub 2020 Jul 9
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Ibrahim S, Froehlich B, Aguilar-Mahecha A, Aloyz R, Poetz O, Basik M, Batist G, Zahedi RP, Borchers CH.听Using two peptide isotopologues as internal standards for the streamlined quantification of low-abundance proteins by immuno-MRM and immuno-MALDI.听Anal Chem. 2020 Aug 12. doi: 10.1021/acs.analchem.0c02157. Online ahead of print.
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Nikolaev EN, Indeykina MI, Brzhozovskiy AG, Bugrova AE, Kononikhin AS, Starodubtseva NL, Petrotchenko EV, Kovalev GI, Borchers CH, Sukhikh GT. Mass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein. J Proteome Res. 2020 Aug 9. doi: 10.1021/acs.jproteome.0c00412. Online ahead of print.
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Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A. The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets. J Thromb Haemost. 2020 Jul 21. doi: 10.1111/jth.15028. Online ahead of print.PMID:32692911
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Scheidt T, Alka O, Gonczarowska-Jorge H, Gruber W, Rathje F, Dell'Aica M, Rurik M, Kohlbacher O, Zahedi RP, Aberger F, Huber CG. Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells. Cell Commun Signal. 2020 Jun 23;18(1):99. doi: 10.1186/s12964-020-00591-0.PMID ;32576205
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Gaither C, Popp R1, Mohammed Y, Borchers CH. Determination of the concentration range for 267 proteins from 21 lots of commercial human plasma using highly multiplexed multiple reaction monitoring mass spectrometry. Analyst. 2020 Apr 7. doi: 10.1039/c9an01893j.
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Grimmer J, Helm S, Dobritzsch D, Hause G, Shema G, Zahedi RP, Baginsky S. Mild proteasomal stress improves photosynthetic performance in Arabidopsis chloroplasts. Nat Commun. 2020 Apr 3;11(1):1662. doi: 10.1038/s41467-020-15539-8.PMID ;32245955
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Liu T, Wang RX, Han J, Qiu YL, Borchers CH, Ling V, Wang JS.Liu T, et al. Changes in plasma bile acid profiles after partial internal biliary diversion in PFIC2 patients. Ann Transl Med. 2020 Mar;8(5):185. doi: 10.21037/atm.2020.01.103.
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Tilburg J, Michaud SA, Maracle CX, Versteeg HH, Borchers CH, van Vlijmen BJM, Mohammed Y. Plasma Protein Signatures of a Murine Venous Thrombosis Model and Slc44a2 Knockout Mice Using Quantitative-Targeted Proteomics. Thromb Haemost. 2020 Mar;120(3):423-436. doi: 10.1055/s-0040-1702229. Epub 2020 Mar 5.;
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Kumm EJ, Pagel O, Gambaryan S, Walter U, Zahedi RP, Smolenski A, Jurk K. The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets. Cells. 2020 Feb 18;9(2):472. doi: 10.3390/cells9020472.PMID: 32085646
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Bhardwaj M, Weigl K, Tikk K, Holland-Letz T, Schrotz-King P, Borchers CH, Brenner H. Multiplex quantitation of 270 plasma听protein markers to identify a signature for early detection of colorectal cancer. Eur J Cancer. 2020 Jan 20;127:30-40. doi: 10.1016/j.ejca.2019.11.021. [Epub ahead of print];
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Shin JJH, Liu P, Chan LJ, Ullah A, Pan J, Borchers CH, Burke JE, Stefan C, Smits GJ, Loewen CJR. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Dev Cell. 2020 Jan 9. pii: S1534-5807(19)31031-7. doi: 10.1016/j.devcel.2019.12.010. [Epub ahead of print].
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2019
Shin JJH, Liu P, Chan LJ, Ullah A, Pan J, Borchers CH, Burke JE, Stefan C, Smits GJ, Loewen CJR. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Dev Cell. 2020 Jan 9. pii: S1534-5807(19)31031-7. doi: 10.1016/j.devcel.2019.12.010.听
听
Sirois I, Aguilar-Mahecha A, Lafleur J, Fowler E, Vu V, Scriver M, Buchanan M, Chabot C, Ramanathan A, Balachandran B, L茅gar茅 S, Przybytkowski E, Lan C, Krzemien U, Cavallone L, Aleynikova O, Ferrario C, Guilbert MC, Benlimame N, Saad A, Alaoui-Jamali M, Saragovi HU, Josephy S, O'Flanagan C, Hursting SD,Richard VR, Zahedi RP, Borchers CH,听Bareke E, Nabavi S, Tonellato P, Roy JA, Robidoux A, Marcus EA, Mihalcioiu C, Majewski J, Basik M. A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability. Mol Cancer Res. 2019 Dec 17. (12):2492-2507. doi: 10.1158/1541-7786.MCR-19-0264.听
听
Silva F, Guirgis A, von Aderkas P, Borchers CH, Thornburg R. LC-MS/MS based comparative proteomics of floral nectars reveal different mechanisms involved in floral defense of Nicotiana spp., Petunia hybrida and Datura stramonium. J Proteomics. 2020 Feb 20.213:103618. doi: 10.1016/j.jprot.2019.103618.
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Mohammed Y, Kootte RS, Kopatz WF, Borchers CH, B眉ller HR, Versteeg HH, Nieuwdorp M, van Mens TE. The intestinal microbiome potentially affects thrombin generation in human subjects. J Thromb Haemost. 2019 Dec 6. doi: 10.1111/jth.14699.听
听
Blank-Landeshammer B, Richard VR, Mitsa G, Marques M, LeBlanc A, Kollipara L, Feldmann I, Couetoux du Tertre M, Gambaro K, McNamara S, Spatz A, Zahedi RP, Sickmann A, Batist G, Borchers CH. Proteogenomics of Colorectal Cancer Liver Metastases: Complementing Precision Oncology with Phenotypic Data. Cancers (Basel). 2019 Dec 1;11(12). pii: E1907. doi: 10.3390/cancers11121907.
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Sobsey CA, Ibrahim S, Richard VR, Gaspar V, Mitsa G, Lacasse V, Zahedi RP, Batist G, Borchers CH. Targeted and Untargeted Proteomics Approaches in Biomarker Development. Proteomics. 2019 Nov 15:e1900029. doi: 10.1002/pmic.201900029. Review.
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Parker CE, Warren Hines MRE, Mocanu V, Greer SF, Borchers CH. Mass Spectrometric Determination of Protein Ubiquitination. Methods Mol Biol. 2019;1934:191-221. doi: 10.1007/978-1-4939-9055-9_13.
Makepeace KAT, Brodie NI, Popov KI, Gudavicius G, Nelson CJ, Petrotchenko EV, Dokholyan NV, Borchers CH. Ligand-induced disorder-to-order transitions characterized by structural proteomics and molecular dynamics simulations. J Proteomics. 2019 Nov 1:103544. doi: 10.1016/j.jprot.2019.103544.听
听
Lategahn J, Keul M, Kl枚vekorn P, Tumbrink HL, Niggenaber J, M眉ller MP, Hodson L, Fla脽hoff M, Hardick J, Grabe T, Engel J, Schultz-Fademrecht C, Baumann M, Ketzer J, M眉hlenberg T, Hiller W, G眉nther G, Unger A, M眉ller H, Heimsoeth A, Golz C, Blank-Landeshammer B, Kollipara L, Zahedi RP, Strohmann C, Hengstler JG, van Otterlo WAL, Bauer S, Rauh D.
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chem Sci. 2019 Oct 4;10(46):10789-10801. doi: 10.1039/c9sc03445e. eCollection 2019 Dec 14.
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听
Popov KI, Makepeace KAT, Petrotchenko EV, Dokholyan NV, Borchers CH. Insight into the Structure of the "Unstructured" Tau Protein. Structure. 2019 Oct 14. pii: S0969-2126(19)30309-0. doi: 10.1016/j.str.2019.09.003.
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Mart铆nez de Paz A, Khajavi L, Martin H, Claveria-Gimeno R, Tom Dieck S, Cheema MS, Sanchez-Mut JV, Moksa MM, Carles A, Brodie NI, Sheikh TI, Freeman ME, Petrotchenko EV, Borchers CH, Schuman EM, Zytnicki M, Velazquez-Campoy A, Abian O, Hirst M, Esteller M, Vincent JB, Malnou CE, Ausi贸 J. MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2. Epigenetics Chromatin. 2019 Oct 10;12(1):63. doi: 10.1186/s13072-019-0298-1.
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Bhardwaj M, Gies A, Weigl K, Tikk K, Benner A, Schrotz-King P, Borchers CH, Brenner H. Evaluation and Validation of Plasma Proteins Using Two Different Protein Detection Methods for Early Detection of Colorectal Cancer. Cancers (Basel). 2019 Sep 25;11(10). pii: E1426. doi: 10.3390/cancers11101426.
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Pires ES, Hardoim CCP, Miranda KR, Secco DA, Lobo LA, de Carvalho DP, Han J, Borchers CH, Ferreira RBR, Salles JF, Domingues RMCP, Antunes LCM. The Gut Microbiome and Metabolome of Two Riparian Communities in the Amazon. Front Microbiol. 2019 Sep 4;10:2003. doi: 10.3389/fmicb.2019.02003. eCollection 2019.
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Mao F, Liu T, Hou X, Zhao H, He W, Li C, Jing Z, Sui J, Wang F, Liu X, Han J, Borchers CH, Wang JS, Li W. Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency. J Biol Chem. 2019 Aug 2;294(31):11853-11862. doi: 10.1074/jbc.RA118.007179. Epub 2019 Jun 14.
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Larina IM, Percy AJ, Yang J, Borchers CH, Nosovsky AM, Grigoriev AI, Nikolaev EN. Publisher Correction: Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts. Sci Rep. 2019 Jun 7;9(1):8570. doi: 10.1038/s41598-019-43121-w.
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Iacobucci C, Piotrowski C, Aebersold R, Amaral BC, Andrews P, Bernfur K, Borchers C, Brodie NI, Bruce JE, Cao Y, Chaignepain S, Chavez JD, Claverol S, Cox J, Davis T, Degliesposti G, Dong MQ, Edinger N, Emanuelsson C, Gay M, G枚tze M, Gomes-Neto F, Gozzo FC, Gutierrez C, Haupt C, Heck AJR, Herzog F, Huang L, Hoopmann MR, Kalisman N, Klykov O, Kuka膷ka Z, Liu F, MacCoss MJ, Mechtler K, Mesika R, Moritz RL, Nagaraj N, Nesati V, Neves-Ferreira AGC, Ninnis R, Nov谩k P, O'Reilly FJ, Pelzing M, Petrotchenko E, Piersimoni L, Plasencia M, Pukala T, Rand KD, Rappsilber J, Reichmann D, Sailer C, Sarnowski CP, Scheltema RA, Schmidt C, Schriemer DC, Shi Y, Skehel JM, Slavin M, Sobott F, Solis-Mezarino V, Stephanowitz H, Stengel F, Stieger CE, Trabjerg E, Trnka M, Vilaseca M, Viner R, Xiang Y, Yilmaz S, Zelter A, Ziemianowicz D, Leitner A, Sinz A. First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study. Anal Chem. 2019 Jun 4;91(11):6953-6961. doi: 10.1021/acs.analchem.9b00658. Epub 2019 May 22.
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Mnatsakanyan R, Markoutsa S, Walbrunn K, Roos A, Verhelst SHL, Zahedi RP. Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique. Nat Commun. 2019 May 16;10(1):2195. doi: 10.1038/s41467-019-10182-4.
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Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Conformational ensemble of native 伪-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations. PLoS Comput Biol. 2019 Mar 27;15(3):e1006859. doi: 10.1371/journal.pcbi.1006859. eCollection 2019 Mar.
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Brunoro GVF, Carvalho PC, Barbosa VC, Pagnoncelli D, De Moura Gallo CV, Perales J, Zahedi RP, Valente RH, Neves-Ferreira AGDC. Differential proteomic comparison of breast cancer secretome using a quantitative paired analysis workflow. BMC Cancer. 2019 Apr 18;19(1):365. doi: 10.1186/s12885-019-5547-y.
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Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tom谩s AM, Southworth DR, Jakob U. Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun. 2019 Feb 8;10(1):659. doi: 10.1038/s41467-019-08565-8.
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Wang R, Sheps JA, Liu L, Han J, Chen PSK, Lamontagne J, Wilson PD, Welch I, Borchers CH, Ling V. Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice. J Lipid Res. 2019 Jan;60(1):85-97. doi: 10.1194/jlr.M088070. Epub 2018 Nov 11.
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2018
Popp R, Li H, Borchers C. 2018 Immuno-MALDI (iMALDI) mass spectrometry for the analysis of proteins in signaling pathways. Expert Rev. Proteomics , 1鈥�8. (doi:10.1080/14789450.2018.1516147)
听
Gonz谩lez Coraspe JA et al. 2018 Biochemical and pathological changes result from mutated Caveolin-3 in muscle. Skelet. Muscle 8, 28. (doi:10.1186/s13395-018-0173-y)
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Zahedi RP, Parker CE, Borchers CH. 2018 Immuno-MALDI-TOF-MS in the Clinic. Clin. Chem. 64, 1271鈥�1272. (doi:10.1373/clinchem.2018.292136)
听
Penn AM et al. 2018 Validation of a proteomic biomarker panel to diagnose minor-stroke and transient ischaemic attack: phase 2 of SpecTRA, a large scale translational study. Biomark. Biochem. Indic. Expo. Response Susceptibility Chem. , 1鈥�11. (doi:10.1080/1354750X.2018.1499130)
听
W枚lter M, Okai CA, Smith DS, Ru脽 M, Rath W, Pecks U, Borchers CH, Glocker MO. 2018 Maternal Apolipoprotein B100 Serum Levels are Diminished in Pregnancies with Intrauterine Growth Restriction and Differentiate from Controls. Proteomics Clin. Appl. , e1800017. (doi:10.1002/prca.201800017)
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Mahdavi S, Jenkins DJA, Borchers CH, El-Sohemy A. 2018 Genetic Variation in 9p21 and the Plasma Proteome. J. Proteome Res. 17, 2649鈥�2656. (doi:10.1021/acs.jproteome.8b00117)
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Mnatsakanyan R, Shema G, Basik M, Batist G, Borchers CH, Sickmann A, Zahedi RP. 2018 Detecting post-translational modification signatures as potential biomarkers in clinical mass spectrometry. Expert Rev. Proteomics 15, 515鈥�535. (doi:10.1080/14789450.2018.1483340)
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Walter C, Gonczarowska-Jorge H, Sickmann A, Zahedi RP, Meisinger C, Schmidt O. 2018 Advanced tools for the analysis of protein phosphorylation in yeast mitochondria. Anal. Biochem. 554, 23鈥�27. (doi:10.1016/j.ab.2018.05.022)
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Bhowmick P, Mohammed Y, Borchers CH. 2018 MRMAssayDB: an integrated resource for validated targeted proteomics assays. Bioinforma. Oxf. Engl. (doi:10.1093/bioinformatics/bty385)
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Pett C et al. 2018 Effective Assignment of 伪2,3/伪2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics. Angew. Chem. Int. Ed Engl. 57, 9320鈥�9324. (doi:10.1002/anie.201803540)
听
Nguyen MTN, Shema G, Zahedi RP, Verhelst SHL. 2018 Protease Specificity Profiling in a Pipet Tip Using 鈥楥harge-Synchronized鈥� Proteome-Derived Peptide Libraries. J. Proteome Res. 17, 1923鈥�1933. (doi:10.1021/acs.jproteome.8b00004)
听
Makhoul S, Walter E, Pagel O, Walter U, Sickmann A, Gambaryan S, Smolenski A, Zahedi RP, Jurk K. 2018 Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets. Nitric Oxide Biol. Chem. 76, 71鈥�80. (doi:10.1016/j.niox.2018.03.008)
听
Parker CE, Borchers CH. 2018 The Special Issue: Clinical Proteomics for Precision Medicine. Proteomics Clin. Appl. 12. (doi:10.1002/prca.201600144)
听
Luehr TC, Koide EM, Wang X, Han J, Borchers CH, Helbing CC. 2018 Metabolomic insights into the effects of thyroid hormone on Rana [Lithobates] catesbeiana metamorphosis using whole-body Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI). Gen. Comp. Endocrinol. 265, 237鈥�245. (doi:10.1016/j.ygcen.2018.02.012)
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Liu T et al. 2018 Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations. Liver Int. Off. J. Int. Assoc. Study Liver 38, 1676鈥�1685. (doi:10.1111/liv.13714)
听
K枚sters M, Leufken J, Schulze S, Sugimoto K, Klein J, Zahedi RP, Hippler M, Leidel SA, Fufezan C. 2018 pymzML v2.0: introducing a highly compressed and seekable gzip format. Bioinforma. Oxf. Engl. 34, 2513鈥�2514. (doi:10.1093/bioinformatics/bty046)
听
Penn AM et al. 2018 Verification of a proteomic biomarker panel to diagnose minor stroke and transient ischaemic attack: phase 1 of SpecTRA, a large scale translational study. Biomark. Biochem. Indic. Expo. Response Susceptibility Chem. 23, 392鈥�405. (doi:10.1080/1354750X.2018.1434681)
听
Shema G, Nguyen MTN, Solari FA, Loroch S, Venne AS, Kollipara L, Sickmann A, Verhelst SHL, Zahedi RP. 2018 Simple, scalable, and ultrasensitive tip-based identification of protease substrates. Mol. Cell. Proteomics MCP 17, 826鈥�834. (doi:10.1074/mcp.TIR117.000302)
听
Perzanowska A, Fatalska A, Wojtas G, Lewandowicz A, Michalak A, Krasowski G, Borchers CH, Dadlez M, Domanski D. 2018 An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung Cancer Pleural Effusions. Proteomics Clin. Appl. 12. (doi:10.1002/prca.201700084)
听
Brodie NI, Huguet R, Zhang T, Viner R, Zabrouskov V, Pan J, Petrotchenko EV, Borchers CH. 2018 Top-Down Hydrogen-Deuterium Exchange Analysis of Protein Structures Using Ultraviolet Photodissociation. Anal. Chem. 90, 3079鈥�3082. (doi:10.1021/acs.analchem.7b03655)
听
Jardim A, Hardie DB, Boitz J, Borchers CH. 2018 Proteomic Profiling of Leishmania donovani Promastigote Subcellular Organelles. J. Proteome Res. 17, 1194鈥�1215. (doi:10.1021/acs.jproteome.7b00817)
听
Mohammed Y, Pan J, Zhang S, Han J, Borchers CH. 2018 ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments. Proteomics Clin. Appl. 12. (doi:10.1002/prca.201600180)
听
Eshghi A, Borchers CH. 2018 Multiple Reaction Monitoring Using Double Isotopologue Peptide Standards for Protein Quantification. Methods Mol. Biol. Clifton NJ 1788, 193鈥�214. (doi:10.1007/7651_2017_112)
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Urao N, Mirza RE, Corbiere TF, Hollander Z, Borchers CH, Koh TJ. 2017 Thrombospondin-1 and disease progression in dysferlinopathy. Hum. Mol. Genet. 26, 4951鈥�4960. (doi:10.1093/hmg/ddx378)
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Han J, Higgins R, Lim MD, Lin K, Yang J, Borchers CH. 2018 Short-Term Stabilities of 21 Amino Acids in Dried Blood Spots. Clin. Chem. 64, 400鈥�402. (doi:10.1373/clinchem.2017.278457)
2017
Gonczarowska-Jorge H, Loroch S, Dell鈥橝ica M, Sickmann A, Roos A, Zahedi RP. 2017 Quantifying Missing (Phospho)Proteome Regions with the Broad-Specificity Protease Subtilisin. Anal. Chem. 89, 13137鈥�13145. (doi:10.1021/acs.analchem.7b02395)
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Bowden JA et al. 2017 Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma. J. Lipid Res. 58, 2275鈥�2288. (doi:10.1194/jlr.M079012)
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Mohammed Y, van Vlijmen BJ, Yang J, Percy AJ, Palmblad M, Borchers CH, Rosendaal FR. 2017 Multiplexed targeted proteomic assay to assess coagulation factor concentrations and thrombosis-associated cancer. Blood Adv. 1, 1080鈥�1087. (doi:10.1182/bloodadvances.2017007955)
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Li H, Popp R, Frohlich B, Chen MX, Borchers CH. 2017 Peptide and Protein Quantification Using Automated Immuno-MALDI (iMALDI). J. Vis. Exp. JoVE (doi:10.3791/55933)
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Popp R et al. 2017 Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors. Anal. Chem. 89, 10592鈥�10600. (doi:10.1021/acs.analchem.7b02934)
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Guarna MM et al. 2017 Peptide biomarkers used for the selective breeding of a complex polygenic trait in honey bees. Sci. Rep. 7, 8381. (doi:10.1038/s41598-017-08464-2)
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M Larina I, Percy AJ, Yang J, Borchers CH, M Nosovsky A, I Grigoriev A, N Nikolaev E. 2017 Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts. Sci. Rep. 7, 8142. (doi:10.1038/s41598-017-08432-w)
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Richard VR, Domanski D, Percy AJ, Borchers CH. 2017 An online 2D-reversed-phase - Reversed-phase chromatographic method for sensitive and robust plasma protein quantitation. J. Proteomics 168, 28鈥�36. (doi:10.1016/j.jprot.2017.07.018)
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Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. 2017 Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations. Sci. Adv. 3, e1700479. (doi:10.1126/sciadv.1700479)
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LeBlanc A et al. 2017 Multiplexed MRM-Based Protein Quantitation Using Two Different Stable Isotope-Labeled Peptide Isotopologues for Calibration. J. Proteome Res. 16, 2527鈥�2536. (doi:10.1021/acs.jproteome.7b00094)
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Li H, Han J, Pan J, Liu T, Parker CE, Borchers CH. 2017 Current trends in quantitative proteomics - an update. J. Mass Spectrom. JMS 52, 319鈥�341. (doi:10.1002/jms.3932)
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Reynolds LA et al. 2017 Enteric Helminths Promote Salmonella Coinfection by Altering the Intestinal Metabolome. J. Infect. Dis. 215, 1245鈥�1254. (doi:10.1093/infdis/jix141)
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Li H, Popp R, Chen M, MacNamara EM, Juncker D, Borchers CH. 2017 Bead-Extractor Assisted Ready-to-Use Reagent System (BEARS) for Immunoprecipitation Coupled to MALDI-MS. Anal. Chem. 89, 3834鈥�3839. (doi:10.1021/acs.analchem.6b04169)
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