³ÉÈËVRÊÓƵ

Resources

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Tools, information & publications

The members of the ³ÉÈËVRÊÓƵ International TB Centre have developed some tools and resources:


Tools


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Cost and Human Resource Calculator for COVID-19 Testing

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This website contains a calculator to estimate the costs and the number of administrative, healthcare, and laboratory personnel required to perform active COVID-19 testing using RT-PCR of high-risk populations, as well as tools to estimate sample size necessary to estimate SARS-CoV-2 prevalence in these populations and the frequency of repeat testing.

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Quality of TB Care – eBook

The ³ÉÈËVRÊÓƵ International TB Centre, Mayo Clinic Center for Tuberculosis and the TBPPM Learning Network are pleased to present a newÌýeBook on Quality of Tuberculosis Care.ÌýThis free eBook, edited by Professors Madhukar Pai & Zelalem Temesgen is a compilation of a series on Quality of TB Care, published in theÌýJournal of Clinical Tuberculosis & Other Mycobacterial Diseases.

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ÌýThe BCG World Atlas Second Edition -ÌýUpdated in 2020

ÌýA Database of Global BCG Vaccination Policies and Practices -Ìý

ÌýThe first of its kind, the BCG World Atlas is a database of policies and practices of the Bacillus Calmette-Guérin (BCG) vaccine, the only licensed vaccine for Ìý
Ìýtuberculosis (TB) from countries all over the world.Ìý


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ÌýThe Online TST/IGRAÌýInterpreter

ÌýThisÌýtool estimates the risk of active tuberculosis for an individual with a tuberculin skin test reaction of ≥5mm, based on his/her clinical profile. It is Ìý
Ìýintended for adults tested with standard tuberculin (5 TUÌýPPDS, or 2 TU RT-23) and/or a commercial Interferon Gamma release assay (IGRA) - Ìý Ìý
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TB skin test training for Health care workers:

YouTube Video:ÌýEnglishÌýÌý-Ìý

YouTube Video: FrenchÌý - Ìý

YouTube Video: Portuguese -Ìý

YouTube Video: Vietnamese -Ìý

YouTube Video: BahasaÌý-Ìý

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PowerPoint Presentation: English -ÌýTuberculin Skin Testing TST Technique TrainingÌý

PowerPoint Presentation: French -ÌýFormation sur l’injection IntraDermo- Réaction à la tuberculine (IDR)

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ÌýIntroducing N-TB, an app for nutritional assessment & counselling of patients with tuberculosis

ÌýThe WHO India recommends that nutritional assessment, counseling and support should be an integral part of TB care. Several actions such as
Ìýguidance documents for patients, support via food rations, and even direct monetary benefits are being implemented. These initiatives require Ìý

Ìýhealthcare providers to be skilled in nutritional assessment and counseling. The first app of its kind,ÌýÌýN-TBÌýenables the classification of the nutritional
Ìýstatus of the patient, gives alerts in case of severe undernutrition and provides management solutions based on the patient's local context.

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ÌýUndernutrition is a common co-morbidity in patients with active TB, which has serious implications for the outcomes of treatment. It is a risk factor Ìý
Ìýfor early death during treatment, drug-induced hepatotoxicity, poor performance status at end of treatment and relapse of disease after successful
Ìýtreatment. Nutritional assessment, counselling and support are now considered as integral part ofÌýtherapy of patients with TB.

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ÌýDownload the free app in Ìý

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MycoHit SoftwareÌý

Graphical user interface for Genomic Sequence Comparison
MycoHit is a JAVA application:Ìý/molepi/mycohit-software


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ÌýContainment Level 3 (CL3) TB FacilityÌý Ìý Ìý Ìý Ìý
ÌýCore Director: Dr. Marcel Behr ÌýÌý
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ÌýThe Facility for TB research meets the highest safety standards defined by Canadian guidelines (PHAC and CFIA).Ìý Work carried out in this
Ìýfacility includes all experimental procedures involving Ìýthe manipulation of live Mycobacterium tuberculosis.Ìý The facility is available to RI-
ÌýMUHC researchers, affiliated collaborators and external researchers working on tuberculosis.ÌýÌý

DATABASE available to members of the TB Centre:Ìý"Understanding the keys to tuberculosis: from exposure to infection, and from infection to disease".
This database was established from 2006 to 2012 from questionnaires and biologic samples.


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Information


outlines steps to scale-up public-private health sector engagement to end TB

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ÌýThe PLOS Tuberculosis ChannelÌý

ÌýYou may have already heard about theÌý, a global forum for tuberculosis related Ìý
Ìýresearch, curated byÌýDr. Soumya Swaminathan andÌýDr. Madhukar Pai. It is a place to stay updated on news, Ìý Ìý Ìý Ìý Ìý discussion and commentary in the field. But have you explored all the contentÌýthe Channel has to offer andÌý
ÌýsubscribedÌýto updates?Ìý

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ÌýThe TBDx Pathway

Ìý The first ever web-basedÌýpathway for tuberculosis (TB) diagnostics (Dx) and adjunct technologiesÌý
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Ìý QuTUB Quality of Tuberculosis careÌý Ìý
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ÌýGHD Online

ÌýIn this new public community on GHDonline, professionals ranging from clinicians, policy-makers, researchers, implementers &
Ìýadvocates share questions, successes and lessons learned to advance the field of global health diagnosticsÌý
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ÌýÌýResources for TB diagnostics developers


Ìý ÌýTB Diagnostics: Top 10 FAQs By Test Developers -ÌýÌý

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Ìý Evidence-Based TB Diagnosis

Ìý AÌýcomprehensive Resource For Evidence Syntheses, Policies, GuidelinesÌýand Research Agendas On TB DiagnosticsÌý
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ÌýA website for learning and teaching epidemiology Ìý

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Publications


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TB Stigma Measurement Guidance
Click here for brochure


ÌýWHO treatment guidelines for isoniazid-resistant tuberculosis: Supplement to the WHO treatment guidelines for drug-resistant tuberculosis
Ìý³ÉÈËVRÊÓƵ Research influences WHO TB policies
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ÌýWHO has just released new clinical guidelines for treatment of INH-resistant TB (based in part on the work of Dr Dick Menzies and others at ³ÉÈËVRÊÓƵ, Montreal). Isoniazid-resistant TB,Ìýwithout concurrent rifampicin Ìý
Ìýresistance, is estimated to occur in about 8% of people with TB globally. A regimen of 6 months rifampicin, ethambutol, pyrazinamide and levofloxacin is now recommended in adults and children diagnosed with this
Ìýtype of drug-resistant TB. Resistance to rifampin and fluoroquinolones should be ruled out before using this regimen.
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ÌýNature Reviews Disease Primer Tuberculosis - over 47,000 downloads!
ÌýWithin the 99th percentile (ranked #762) of 252,738 tracked articles of a similar age in all journals
ÌýWithin the 95th percentile (ranked #1) of 24 tracked articles of a similar age in Nature Reviews Disease Primers

An international group of top TB experts from several leading institutions, coordinated by the ³ÉÈËVRÊÓƵ International TB Centre, published a primer on tuberculosis (TB) in the journal Nature Reviews Disease Primers.Ìý

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ÌýLet's Talk TB - 3rd Edition (2018)Let's Talk TB is a book on the current best practices in TB diagnosis and treatment available for free for all GPs and private practitioners in Ìý
ÌýIndia and other high-burden countries.
ÌýClick here for free download:

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Target product profilesÌý(TPPs) for priority diagnostics are available at:Ìý

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Click here for list

  • . FIND,Ìý³ÉÈËVRÊÓƵ International TB CentreÌýandÌýUNITAID.ÌýOctober 2015.
  • Ìý- 4th edition. UNITAID. October 2015.
  • - 2nd edition. UNITAID. October 2014.
  • Ìý- 3rd edition. UNITAID. September 2014.
  • Ìý- semi-annual update. UNITAID. December 2013.
  • Ìý- 2nd edition. UNITAID. July 2013.
  • Ìý- semi-annual update. UNITAID. December 2012.
  • . UNITAID. July 2012.

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TB diagnosticsÌýmarket analyses:

  • .ÌýInt J Tuberc Lung DisÌý2016.
  • 2.ÌýInt J Tuberc Lung DisÌý2016.Ìý
  • ÌýLancet Global HealthÌý2016.
  • ÌýFINDÌý2015
  • J Infect Dis 2015.
  • . Int J Tuberc Lung Dis 2015.
  • ? Eur Respir J 2014.
  • 2. PLoS ONE 2014.

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