The labs of Dr John White and听Dr Jorg Fritz are seeking for an highly motivated postdoctoral fellow, who听can begin in May or June 2018. The postdoc should have expertise in flow cytometry and mouse work,听and听competence in Bioinformatics听would听be an asset. The听successful candidate听will work in both lab environments.听
2017
-Dimitrov V, White JH.,,听Mol Cell Endocrinol. 2017 Sep 15
-Iu M, Zago M, Rico de Souza A, Bouttier M, Pareek S, White JH, Hamid Q, Eidelman DH, Baglole CJ.,听,听Free Radic Biol Med. 2017 Jul;
2016
-听White JH.,听,听J Steroid Biochem Mol Biol. 2016 Dec 23. 听Review.
-听Bouttier M, Laperriere D, Memari B, Mangiapane J, Fiore A, Mitchell E, Verway M, Behr MA, Sladek R, Barreiro LB, Mader S, White JH., 听Nucleic Acids Res. 2016 Dec 15;
-听Boukhaled GM, Cordeiro B, Deblois G, Dimitrov V, Bailey SD, Holowka T, Domi A, Guak H, Chiu HH, Everts B, Pearce EJ, Lupien M, White JH, Krawczyk CM.,听T,听Cell Rep. 2016 Aug 16;
-听Jensen ME, Mailhot G, Alos N, Rousseau E, White JH, Khamessan A, Ducharme FM,听听Trials. 2016 Jul 26
- Dimitrov V, White JH., .,听Am J Clin Nutr. 2016 May;103(5):1195-6. doi: 10.3945/ajcn.116.134247.听
2015
- Memari B, Bouttier M, Dimitrov V, Ouellette M, Behr MA, Fritz JH, White JH. . J Immunol. 2015 Nov 1
- Dimitrov V, White JH. . J Steroid Biochem Mol Biol. 2015 Sep. Review.
- Fekrmandi F, Wang TT, White JH. . Sci Rep. 2015 Aug 13;5:13002. doi: 10.1038/srep13002.
- Kaldre D, Wang TT, Fischer J, White JH, Gleason JL. . Bioorg Med Chem. 2015 Aug.
- White JH. JAK3 talks to renal 25-hydroxyvitamin D 1alpha-hydroxylase.听Kidney Int. 87(4):678-9.
- Goltzman D, Hendy GN, White JH.听Vitamin D and its receptor during late development.听Biochim Biophys Acta. 1849(2):171-180.
2014
- Dimitrov V, Salehi-Tabar R, An BS, White JH. . J Steroid Biochem Mol Biol. 2014 Oct
- Calderon MR, Verway M, Benslama RO, Birlea M, Bouttier M, Dimitrov V, Mader S, White JH. Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1.听Nucleic Acids Res. 42(11):7012-27
2013
- White JH.听Vitamin D and human health: more than just bone. Nat Rev Endocrinol. 9(10):623
- Dimitrov V, Salehi-Tabar R, An BS, White JH.听Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: Insights into calcium homeostasis, immune system regulation and cancer chemoprevention. J Steroid Biochem Mol Biol. 109, 18827-18832
- Verway, M., Bouttier, M., Wang, T.T., Carrier, M., Calderon, M., An, B.-S., Devemy, E., McIntosh, F., Divangahi, M., Behr, M.A. and White, J.H.听Vitamin D induces interleukin-1b expression: Paracrine macrophage-epithelial signaling controls M. tuberculosis infection. PLoS Pathogens 9 (6):听e1003407. doi: 10.1371/journal.ppat.1003407
2012
Salehi-Tabar, R., Nguyen-Yamamoto, L., Tavera-Mendoza, L.E., Quail, T., Dimitrov, V., An, B.-S., Glass, L., Goltzman, D. and White, J.H.听The vitamin D receptor as a master regulator of the cMYC/MXD1 network. Proc. Nat. Acad. Sci. U.S.A. 109, 18827-32.
Voted one of the top 10 cancer research stories of 2012 by the Canadian Cancer Society.
Fisher, J., Wang, T.T., Kaldre, D., Rochel, N., Moras, D., White, J.H., Gleason J.L.听Synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition. Chemistry & Biology 19, 963-71.
2010
An, B.-S., Tavera-Mendoza, L.E., Dimitrov, V., Wang, X., Calderon, M., Wang, H.-J., and White, J.H.听Stimulation of SIRT1-regulated FoxO protein function by the ligand-bound vitamin D receptor. Mol. Cell. Biol. 30, 4890-4900.
Wang, T.T, Dabbas, B., Laperriere, D., Bitton, A., Tavera-Mendoza, L.E., Soualhine, H., Dionne, S., Servant, M.J., Bitton, A., Seidman, E., Mader, S., Behr, M. and White, J.H.听Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-beta defensin 2 innate immune pathway defective in Crohn鈥檚 disease. J. Biol. Chem. 285, 2227 鈥� 2231.
Recommended twice by the Faculty of 1000; Featured in 鈥楳ontr茅al en sant茅鈥� magazine, Fall 2010.
2003-2009
Palijan, A., Fernandes, I., Verway, M., Kourelis, M., Bastien, Y., Tang, L., Tavera-Mendoza, L.E., Li, Z., Bertos, N.R., Bourdeau, V., Mader, S., Yang, X.J. and White, J.H. (2009) Function of HDAC6 as a cofactor of nuclear receptor corepressor LCoR. J. Biol. Chem. 284, 30264-74.
Tavera-Mendoza, L.E., Quach, T., Dabbas, B., Hudon, J., Liao, X., Palijan, A., Gleason, J.L., and White, J.H. (2008) Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist. Proc. Nat. Acad. Sci. U.S.A. 105, 8250-55.
Tavera-Mendoza LE, White JH. (2007) Cell defenses and the sunshine vitamin. Sci Am. 297(5):62-5, 68-70, 72.
Tavera-Mendoza, L., Wang, T.T., Lallemant, B., Zhang, R., Nagai, Y., Bourdeau, V., Ramiro Calderon, M., Desbarats, J., Mader, S., and White, J.H. (2006) Convergence of vitamin D and retinoic acid signaling at a common hormone response element. EMBO Rep. 7, 180-185.
Wang, T.T., Tavera-Mendoza, L., Laperriere, D., Nagai, Y., Burton MacLeod, N., Libby, E., Zhang, R., Bourdeau, V., Konstorum, A., Lallemant, B., Mader, S. and White, J.H. (2005) 听Large-scale in silico and microarray-based genomic screening of 1,25-dihydroxyvitamin D3 target genes. Mol. Endocrinol. 19, 2685-95.
Wang, T.T., Nestel, F., Bourdeau, V., Nagai, Y., Wang, Q., Wu, J., Tavera-Mendoza, L., Lin, R., Hanrahan, J.H., Mader, S. and White, J.H. 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J. Immunol. (Cutting Edge Report). 173, 2909-12.
Bourdeau, V., Deschenes, J., Metivier, R., Nagai, Y., Nguyen, D., Bretschneider, N., Gannon, F., White, J.H. and Mader S. (2004) Genome-wide identification of high affinity estrogen response elements in human and mouse. Mol. Endocrinol. 18, 1411-1427.
Fernandes, I, Bastien, Y., Wai, T., Nygard, K., Lin, R., Cormier, O., Lee, H.S., Eng, F., Bertos, N.R., Pelletier, N., Mader, S., Han V.K.M., Yang, X.J. and White, J.H. (2003) Ligand-dependent corepressor LCoR functions by histone deacetylase-dependent and 鈥搃ndependent mechanisms. Molecular Cell, 11, 139-50.
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Iu M, Zago M, Rico de Souza A, Bouttier M, Pareek S, White JH, Hamid Q, Eidelman DH, Baglole CJ.
Free Radic Biol Med. 2017 Jul;108:19-31. doi: 10.1016/j.freeradbiomed.2017.02.045. Epub 2017 Feb 27.